{"id":13,"date":"2017-01-05T19:41:32","date_gmt":"2017-01-05T19:41:32","guid":{"rendered":"http:\/\/wordpress.uchospitals.edu\/basu-lab\/?page_id=13"},"modified":"2025-04-29T20:08:03","modified_gmt":"2025-04-29T20:08:03","slug":"publication","status":"publish","type":"page","link":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/publication\/","title":{"rendered":"Publication"},"content":{"rendered":"<p>Y. Zhao, R. Zhou, Z. Mu, P. Carbonetto, X. Zhong, B. Xie, K. Luo, C. M. Cham, J. Koval, X. He, A. W. Dahl, X. Liu, E. B. Chang, A. Basu, S. Pott, <em>Cell-type-resolved chromatin accessibility in the human intestine identifies complex regulatory programs and clarifies genetic associations in Crohn&#8217;s disease<\/em>, medRxiv (2024), <a href=\"https:\/\/doi.org\/10.1101\/2024.12.10.24318718\">https:\/\/doi.org\/10.1101\/2024.12.10.24318718<\/a><\/p>\n<p>R. Zhou, B. Xie, J. Liu, Y. Zhao, J. Koval, C. M. Cham, J. Pekow, C. Weber, E. B. Chang, A. Basu, Epithelia mediate inflammation with myeloid cells in Crohn\u0393\u00c7\u00d6s disease patients under treatment, bioRxiv (2025), <a href=\"https:\/\/doi.org\/10.1101\/2025.03.26.645552\">https:\/\/doi.org\/10.1101\/2025.03.26.645552<\/a><\/p>\n<p>M. Weigert, Y. Li, L. Zhu, H. Eckart, P. Bajwa, R. Krishnan, S. Ackroyd, R. Lastra, A. Bilecz, A. Basu, E. Lengyel, M. Chen, &#8220;A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause&#8221;<em>, <\/em><a href=\"https:\/\/doi.org\/10.1038\/s41467-024-55440-2\"><i data-test=\"journal-title\">Nature Communications<\/i> <b data-test=\"journal-volume\">16<\/b>, <span data-test=\"article-number\">372<\/span> (<span data-test=\"article-publication-year\">2025<\/span>)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2025\/04\/Weigert_NatComm2025.pdf\">pdf<\/a>)<\/p>\n<p>Y. Zhao, R. Zhou, B. Xie, C. Y. Liu, M. Kalski, C. M. Cham, J. Koval, C. R. Weber, D. T. Rubin, M. Sogin, S. Crosson, J. Huang, A. Fiebig, S. Dalal, E. B. Chang, A. Basu, S. Pott*, &#8220;Multiomic analysis reveals cellular, transcriptomic and epigenetic changes in intestinal pouches of ulcerative colitis patients&#8221;, <a href=\"https:\/\/doi.org\/10.1038\/s41467-025-56212-2\"><em>Nature Communications,<\/em> <strong>16<\/strong>, 904 (2025)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2025\/04\/Weigert_NatComm2025.pdf\">pdf<\/a>)<\/p>\n<p>B. Xie, S. Olalekan, R. Back, N. Ashitey, H. Eckart, A. Basu, \u0393\u00c7\u00a3Comparing the tumor microenvironment of solid tumors of different primary and metastatic ovarian cancer histotypes at single cell resolution\u0393\u00c7\u00a5, <a href=\"https:\/\/doi.org\/10.3389\/fcell.2023.1297219\"><span class=\"il\"><em>Frontiers<\/em><\/span><em> in Cell and Developmental Biology, Sec. Cell Adhesion and Migration<\/em>, <strong>11<\/strong> (2023)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2025\/04\/Xie_PrimaryVsMetastatic_frontiers2023.pdf\">pdf<\/a>)<\/p>\n<p>A. Selewa, K. Luo, M. Masney, L. Smith, C. Tang, H. Eckart, I. Moskowitz, A. Basu, X. He, S. Pott, &#8220;Single-cell genomics improves the discovery of risk variants and genes of cardiac traits&#8221;, <a href=\"https:\/\/doi.org\/10.1038\/s41467-023-40505-5\"><em>Nature Communications<\/em>, <strong>14<\/strong>, 4999 (2023)<\/a>, (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2023\/09\/selewa_NatComm2023.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">S. Baisiwala, S. Budhiraja, E. Perrault, A. Zolp, K. Nandoliya, J. Miska, L. Chen, C. Park, M. Saathoff, C. Dmello, J. Shireman, P. Lin, J. Duffy, I. Balyasnikova, J. David, C. Horbinski, S. Pott, A. Basu, A. Sonabend, A. Ahmed, &#8220;Ribonucleotide Reductase Regulatory Subunit M2 Drives Glioblastoma TMZ-Resistance through Modulation of dNTP Production&#8221;<em>,<\/em> <a href=\"https:\/\/doi.org\/10.1126\/sciadv.ade7236\"><em>Science Advances<\/em>, <strong>9<\/strong>, eade7236 (2023)<\/a>, (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2023\/09\/atique_sciadv2023.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">P. V. K. Nittala, A. Hohreiter, E. R. Linhard, R. Dohn, S. Mishra, A. Konda, R. Divan, S. Guha, A. Basu, &#8220;Integration of silicon chip microstructures for in-line microbial cell lysis in soft microfluidics&#8221; <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2023\/lc\/d2lc00896c\"><em>Lab on a Chip<\/em>, <strong>23<\/strong>, 2327-2340 (2023) <\/a>(<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2023\/09\/Nittala_LoC2023.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. R. Haltom, W. E. Hassen, J. Hensel, J. Kim, H. Sugimoto, B. Li, K. M. McAndrews, M. R. Conner, M. L. Kirtley, X. Luo, B. Xie, O. V. Volpert, S. Olalekan, N. Maltsev, A. Basu, V. S. LeBleu, R. Kalluri, &#8220;Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma&#8221; <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2773041722000099\"><em>Extracellular Vesicle<\/em>, <strong>1<\/strong>, 100014 (2022)<\/a>(<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2023\/04\/Exosome2023.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Moya-Rodr\u251c\u00a1guez, B. Xie, D. Cook, M. Klineberg, S. Nathan, M. Hammes, A. Basu, &#8220;Creating Patient-Specific Vein Models to Characterize Wall Shear Stress in Hemodialysis Population&#8221;, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2001037022004573\"> <em> Computational and Structural Biotechnology Journal <\/em>, <strong>20<\/strong>, 5729 (2022) <\/a>(<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2022\/10\/Andres2022.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">E. Lengyel, Y. Li, M. Weigert, L. Zhu, H. Eckart, M. Javellana, S. Ackroyd, J. Xiao, S. Olalekan, D. Glass, S. Iyer, A. J. Bilecz, R. Lastra, M. Chen, A. Basu, &#8220;A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing&#8221;, <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.08.04.502826v1\"><em>BioRXiv, doi: https:\/\/doi.org\/10.1101\/2022.08.04.502826 <\/em> <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2022\/08\/lengyel_biorxiv_v1.pdf\">pdf<\/a>); <em>Cell Reports<\/em>, <strong>41<\/strong>(12), 111838 (2022)<\/p>\n<p class=\"Achievement\">A. Selewa, K. Luo, M. Wasney, L. Smith, C. Tang, H. Eckart, I. Moskowitz, A. Basu, X. He, S. Pott, &#8220;Single-cell genomics improves the discovery of risk variants and genes of cardiac traits&#8221;, <em>MedRXiv,<\/em> <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2022.02.02.22270312v1\">https:\/\/doi.org\/10.1101\/2022.02.02.22270312 <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2022\/12\/Selewa_medrxiv2022.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">R. Dohn, B. Xie, R. Back, A. Selewa, H. Eckart, R. Prusty Rao, A. Basu, &#8220;mDrop-seq: Massively parallel single-cell RNA-seq of <em>Saccharomyces cerevisiae<\/em> and <em>Candida albicans<\/em>&#8220;, <a href=\"https:\/\/www.mdpi.com\/2076-393X\/10\/1\/30#\"><em>Vaccines,<\/em> <strong>10<\/strong>(1), 30 (2022)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2021\/12\/Dohn_vaccines2022.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">V. Phan, M. van Gent, N. Drayman, A. Basu, M. U. Gack, S. Tay, &#8220;High-throughput RNA sequencing of paraformaldehyde-fixed single cells&#8221;, <a href=\"https:\/\/www.nature.com\/articles\/s41467-021-25871-2\"> <em>Nature Communications<\/em>, <strong>12<\/strong>, 5636 (2021) <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2022\/01\/Phan2021.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">M. Hammes, A. Moya-Rodriguez, C. Bernstein, S. Nathan, R. Navuluri, A. Basu, &#8220;Computational modeling of the cephalic arch predicts hemodynamic profiles in patients with brachiocephalic fistula access receiving hemodialysis&#8221;, <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0254016\"> <em>PLoS ONE<\/em>, <strong>16<\/strong>(7): e0254016 (2021)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2021\/06\/Merged_draft.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">S. Olalekan, B. Xie, R. Back, H. Eckart, A. Basu, &#8220;Characterizing the tumor microenvironment of metastatic ovarian cancer by single cell transcriptomics&#8221;, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124721005076\"><em> Cell Reports<\/em>, <strong>35<\/strong>, 109165 (2021) <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2021\/06\/abasu_Olalekan_CellReports.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">M. Rowton, C. Perez-Cervantes, A. Rydeen, S. Hur, J. Jacobs-Li, N. Deng, E. Lu, A. Guzzetta, J. D. Steimle, A. Hoffmann, S. Lazarevic, X. H. Yang, C. Kim, S. Yu, H. Eckart, S. Iddir, M. Koska, E. Hanson, S. S. Chan, D. J. Garry, M. Kyba, A. Basu, K. Ikegami, S. Pott, I. P. Moskowitz, &#8220;Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages&#8221;,<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1534580722005950\"><em>Developmental Cell<\/em>, <strong>57<\/strong>, 2181 (2022) <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2022\/10\/Rowton_DevCell2022.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Guzzetta, M. Koska, M. Rowton, J. Kweon, H. Hidalgo, H. Eckhart, A. Moon, A. Basu*, M. Bressan*, S. Pott*, I. Moskowitz*, &#8220;A Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation&#8221;, <a href=\"https:\/\/www.pnas.org\/content\/117\/27\/15712\"><em>PNAS,<\/em> <strong>117<\/strong>, 15712 (2020) <\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2021\/06\/abasu_guzetta_pnas.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Selewa, R. Dohn, H. Eckart, S. Lozano, B. Xie, E. Gauchat, R. Elorbany, K. Rhodes, J. Burnett, Y. Gilad, S. Pott, A. Basu, &#8220;Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation&#8221;, <a href=\"https:\/\/www.nature.com\/articles\/s41598-020-58327-6\"><i data-test=\"journal-title\">Scientific Reports,<\/i> <b data-test=\"journal-volume\">10<\/b>, 1535 (2020) (<\/a><a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2020\/02\/Selewa_ScientificReports_2020.pdf\">pdf<\/a><a href=\"https:\/\/www.nature.com\/articles\/s41598-020-58327-6\">)<\/a><\/p>\n<p class=\"Achievement\">M. Hammes, R. L. McGill, A. Basu, T. Blicharski, K. Delaney, &#8220;Hemodynamic effects of hemodialyzer pump speed on arteriovenous fistulas&#8221;, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30526815#\"><em>Clinical Nephrology<\/em>, <strong>91<\/strong>, 138 (2019)<\/a> (pdf)<\/p>\n<p class=\"Achievement\">N. Habib*, I. Avraham-Davidi*, A. Basu*, T. Burks, K. Shekhar, M. Hofree, S. R. Choudhury, F. Aguet, E. Gelfand, K. Ardlie, D. A. Weitz, O. Rozenblatt-Rosen, F. Zhang &amp; A. Regev, &#8220;Massively parallel single nucleus RNA -seq with DroNc-seq&#8221;, <a href=\"https:\/\/www.nature.com\/articles\/nmeth.4407\"><em>Nature Methods<\/em>, 955 (2017)<\/a> (<a href=\"http:\/\/medpress.bsd.uchicago.edu\/basu-lab\/files\/2017\/09\/Habib_et_al-2017-Nature_Methods.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">Y. Tao, A. Rotem, H. Zhang, C. B. Chang, A. Basu, A. O. Kolawole, S. A. Koehler, Y. Ren, J. S. Lin, J. M. Pipas, A. B. Feldman, C. E. Wobus and D. A. Weitz, &#8220;Rapid, targeted and culture-free viral infectivity assay in drop-based microfluidics&#8221;, <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2015\/LC\/C5LC00556F#!divAbstract\"><em>Lab on a Chip<\/em>, <span class=\"cit\"><strong>15<\/strong>, 3934 (2015) <\/span><\/a>(<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_viralinfectivity.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">E.  Z. Macosko, A. Basu, R. Satija, J. Nemesh, K. Shekhar, M. Goldman, I. Tirosh, A.  R. Bialas, N. Kamitaki, E.  M. Martersteck, J. J. Trombetta, D. A. Weitz, J. R. Sanes, A. K. Shalek, A. Regev and S. A. McCarroll, &#8220;Highly Parallel Genome-Wide Expression Profiling of Individual Cells Using Nanoliter Droplets&#8221;, <a href=\"https:\/\/www.cell.com\/fulltext\/S0092-8674(15)00549-8\"><em>Cell<\/em>, <strong>161<\/strong>, 1202 (2015) <\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_dropseq_0.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Rotem, O. Ram, N. Shoresh, R. A. Sperling, M. Schnall-Levin, H. Zhang, A. Basu, B. E. Bernstein and D. A. Weitz, &#8220;High-Throughput Single-Cell Labeling (Hi-Scl) for Rna-Seq Using Drop-Based Microfluidics&#8221;, <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0116328\"> <em>PLoS ONE<\/em>, <strong>10<\/strong>, e0116328 (2015)<\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_hiscl.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Basu, Y. Xu, T. Still, P. E. Arratia, Z. Zhang, K. N. Nordstrom, J. M. Rieser, J. P. Gollub, D.J. Durian and A. G. Yodh, &#8220;Rheology of Soft Colloids Across the Onset of Rigidity: Scaling Behavior, Thermal, and Non-thermal Responses&#8221;, <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2014\/sm\/c3sm52454j\"> <em>Soft Matter<\/em>, <strong>10<\/strong>(17), 3027 (2014) <\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_jamming.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Guha and A. Basu, &#8220;Role of rare earth oxide nanoparticles (CeO2 and La2O3) in suppressing the photobleaching of fluorescent organic dyes&#8221;, <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10895-014-1375-2\"> <em>Journal of Fluorescence<\/em>, <strong>24<\/strong>(3), 683 (2014)<\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_photobleaching.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">Q. Wen, A. Basu, P. A. Janmey and A. G. Yodh, &#8220;Non-affine deformations in polymer hydrogels&#8221;, <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2012\/sm\/c2sm25364j\"><em>Soft Matter<\/em>, <strong>8<\/strong>, 8039 (2012) <\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_nonaffine_review.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">A. Basu, Q. Wen, X. Mao, T. C. Lubensky, P.A. Janmey and A. G. Yodh, &#8220;Non-affine displacements in flexible polymer networks&#8221;, <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/ma1026803\"> <em>Macromolecules<\/em>, <strong>44,<\/strong> 1671 (2011) <\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_nonaffine_pa.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">K. N. Nordstrom, E. Verneuil, P. E. Arratia, A. Basu, Z. Zhang, A. G. Yodh, J. P. Gollub and D. J. Durian, &#8220;Microfluidic rheology of soft colloids above and below jamming&#8221;, <a href=\"https:\/\/journals.aps.org\/prl\/abstract\/10.1103\/PhysRevLett.105.175701\"> <em>Physical Review Letters<\/em>, <strong>105<\/strong>, 175701 (2010)<\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_jamming_micro.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">Q. Wen, A. Basu, J. Winer, A. Yodh and P. Janmey, &#8220;Local and global deformations in a strain-stiffening fibrin gel&#8221;, <a href=\"https:\/\/iopscience.iop.org\/article\/10.1088\/1367-2630\/9\/11\/428\"> <em>New Journal of Physics<\/em>, <strong>9<\/strong> 428 (2007)<\/a> (<a href=\"http:\/\/scholar.harvard.edu\/files\/abasu\/files\/abasu_nonaffine_fibrin.pdf\">pdf<\/a>)<\/p>\n<p class=\"Achievement\">\n","protected":false},"excerpt":{"rendered":"<p>Y. Zhao, R. Zhou, Z. Mu, P. Carbonetto, X. Zhong, B. Xie, K. Luo, C. M. Cham, J. Koval, X. He, A. W. Dahl, X. Liu, E. B. Chang, A. Basu, S. Pott, Cell-type-resolved chromatin accessibility in the human intestine identifies complex regulatory programs and clarifies genetic associations in Crohn&#8217;s disease, medRxiv (2024), https:\/\/doi.org\/10.1101\/2024.12.10.24318718 R. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/publication\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Publication&#8221;<\/span><\/a><\/p>\n","protected":false},"author":233,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-13","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/pages\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/users\/233"}],"replies":[{"embeddable":true,"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":8,"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":1267,"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/pages\/13\/revisions\/1267"}],"wp:attachment":[{"href":"https:\/\/medpress.bsd.uchicago.edu\/basu-lab\/wp-json\/wp\/v2\/media?parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}